Blondie was a radio situation comedy adapted from the long-run Blondie comic strip by Chic Young. The radio program had a long run on several networks from 1939 to 1950.

After Penny Singleton was cast in the title role of the feature film Blondie (1938), co-starring with Arthur Lake as Dagwood, she and Lake repeated their roles December 20, 1938, on The Bob Hope Show. The appearance with Hope led to their own show, beginning July 3, 1939, on CBS as a summer replacement for The Eddie Cantor Show. However, Cantor did not return in the fall, so the sponsor, Camel Cigarettes chose to keep Blondie on the air Mondays at 7:30pm.